SPINAL CORD INJURY

Shared and distinct antispastic effects of electrical and pharmacological neuromodulation

• Objective: To compare the antispastic effects of common medications with electrical neuromodulation.
• Lead Investigator: Matthias J. Krenn, Ph.D.
• Related Publications: New
• Funding: Craig H. Neilsen Foundation
• Detailed information: click here
• Status: RECRUITING. If you are interested in participating, click here

Transcutaneous spinal stimulation for reducing lower limb spasticity in chronic spinal cord injury

• Objective: To determine if electrical neuromodulation can reduce muscle stiffness and spasms in people with spinal cord injury in a home-based therapy setting.
• Lead Investigator: Matthias J. Krenn, Ph.D.
• Related Publications: New
• Funding: Paralyzed Veterans of America
• Detailed information: click here
• Status: RECRUITING. If you are interested in participating, click here​

Electrical neuromodulation for modifying the spinal network involved in spasticity

• Objective: To examine whether electrical stimulation can reduce muscle stiffness and spasms in people with spinal cord injury.
• Principal Investigator: Matthias J. Krenn, Ph.D.
• Related Publications: New
• Funding: Mississippi Center for Clinical and Translational Research, NIH
• Detailed information: click here
• Status: RECRUITING. If you are interested in participating, click here

Neurophysiologic investigation of inter-limb connectivity after SCI

• Objective: Investigate residual connectivity between upper and lower limbs in complete SCI
• Lead Investigator: Dobrivoje S. Stokic, MD, DSc
• Related Publications: New
• Funding: The Wilson Research Foundation, Jackson, MS
• Status: Recruiting, if interested to participate, click here

Effect of pulse characteristics used for transcutaneous spinal stimulation on short-latency responses in lower limb muscles

• Objective: To determine the excitability of spinal reflexes.
• Principal Investigator: Matthias J. Krenn, Ph.D.
• Related Publications: [PubMed]
• Funding: Wings for Life USA – Spinal Cord Research Foundation Inc.
• Detailed information: click here
• Status: Closed

Defining the capacity of the lumbosacral network for neuromodulation in humans with spinal cord injury

• Objective: To determine how electrical neuromodulation affects the responsiveness of the lumbosacral network in people with spinal cord injuries. We aim to understand how spinal reflexes can demonstrate the potential for neuromodulation at different stimulation intensities and frequencies.
• Principal Investigator: Matthias J. Krenn, Ph.D.
• Related Publications: New
• Funding: Wings for Life USA – Spinal Cord Research Foundation Inc.
• Detailed information: click here
• Status: Closed